Category Archives: Research
Infection of maize roots by C. graminicola
Several Green Fluorescent Protein (GFP) tagged strains of C. graminicola were prepared in my laboratory and used to study the plant root colonization process. We have shown that the leaf pathogen C. graminicola is also able to infect and colonize … Continue reading
Transcriptional Profiling During Anthracnose Disease Development
The value of differential gene expression studies as tools to dissect the biological mechanisms is well established. There is a growing list of fungal and plant genes that are reported to be expressed specifically during pathogenesis. One of the main drawbacks … Continue reading
Identification of Pathogenicity Genes in Colletotrichum graminicola
A variety of techniques are being employed to understand the genetic basis of pathogenicity of filamentous fungi to plants. Virtually all genetic methods are centered on the characterization of individual genes and gene products through the construction of null mutants, … Continue reading
Functional Annotation of Proteins
As genome sequences of pathogenic fungi become increasingly available, our primary challenge is the integration of existing knowledge about gene function with the genome sequences. The genomes of more than 30 fungi have been sequenced, however our knowledge of the … Continue reading
Conservation of Synteny in Filamentous Fungi
My initial work with the M. grisea and N. crassa genomes reveals that many segments of conserved synteny (groups of orthologous genes that are found in close proximity to one another) can be found between the two species despite more … Continue reading